Check you Antihistamine

LD50

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First generation antihistaminesSecond generation antihistamines
Cetirizine (Zyrtec, Allecet, Texa, Zetop)
Loratadine (Clarityne, Allergex-non drowsy, AP Loratidine, Pollentyme);
Active ingredient and examples of trade names -->Chlorpheniramine (Allerhist®, Allergex®)Desloratadine (Deselex, Dazit, Adco-Desloratidine, Clarex 5, Neolori;
Promethazine (Daralix®, Prohist®, Lenazine®, Phenergan®)Fexofenadine (Telfast, Fexo, Fastway, Tellerge);
Levocetirizine (Xyzal, Allerway 5, Cetizal 5);
Rupatadine (Rupanse);
Levocabastine (Sinumax allergy nasal spray);
Azelastine nasal spray (Rhinolast)
Researched in childrenLess extensively researchedExtensively researched
SedativeVery SedativeLess sedative or not sedative
Duration of actionShort acting (need to be taken frequently: three to four times per day)Long acting (can be taken once daily)
Dry mouth and constipationCommon occurrenceLess common
Hyperactivity, insomnia, convulsions, reduction in “deep” sleepPotential existsLess likely to occur
Increased appetitePotential existsLess likely to occur
Serious side effects when taken with other drugs (e.g. antifungals, erythromycin and azithromycin antibiotics)CommonUnlikely to occur
Poor concentration and work or school, impaired learningCommonly describedLess likely to occur
Lethal in overdoseHas been described in infants and young childrenNo fatalities described
 

biometrics

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Oct 17, 2019
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20,354
First generation antihistaminesSecond generation antihistamines
Cetirizine (Zyrtec, Allecet, Texa, Zetop)
Loratadine (Clarityne, Allergex-non drowsy, AP Loratidine, Pollentyme);
Active ingredient and examples of trade names -->Chlorpheniramine (Allerhist®, Allergex®)Desloratadine (Deselex, Dazit, Adco-Desloratidine, Clarex 5, Neolori;
Promethazine (Daralix®, Prohist®, Lenazine®, Phenergan®)Fexofenadine (Telfast, Fexo, Fastway, Tellerge);
Levocetirizine (Xyzal, Allerway 5, Cetizal 5);
Rupatadine (Rupanse);
Levocabastine (Sinumax allergy nasal spray);
Azelastine nasal spray (Rhinolast)
Researched in childrenLess extensively researchedExtensively researched
SedativeVery SedativeLess sedative or not sedative
Duration of actionShort acting (need to be taken frequently: three to four times per day)Long acting (can be taken once daily)
Dry mouth and constipationCommon occurrenceLess common
Hyperactivity, insomnia, convulsions, reduction in “deep” sleepPotential existsLess likely to occur
Increased appetitePotential existsLess likely to occur
Serious side effects when taken with other drugs (e.g. antifungals, erythromycin and azithromycin antibiotics)CommonUnlikely to occur
Poor concentration and work or school, impaired learningCommonly describedLess likely to occur
Lethal in overdoseHas been described in infants and young childrenNo fatalities described
The table seems a bit messed up. What are we looking at?

Edit: ok I get it. First column are the attributes for the second and third column.
 

LD50

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The table seems a bit messed up. What are we looking at?
Not the best layout I agree
You can't make out? top half has the brands with active ingredients in bold.
Bottom half gives more info on each of the two catagories
Basically your second generation antihistamines are better - So Allergex is kak - Texa is preferred
 

LD50

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I think I need some right now.

Sneezed like 5 times in the last minute.
Same. Used to get hayfever every damn year from end Sept. Bad. Needed injection since tabs were ineffective. Then all of a sudden it stopped for 3 years until now. Eyes and nose burning and itching, sneezing uncontrollably...
Fuck! I hate this
 

BloodrayneZA

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I was recommended Cetirizine Hypochloride by a ENT specialist in SA and in the UK, the pharmacists are trained to find what is needed. They even make sure the medication doesn't cause any bad interactions between my prescribed meds.

@LD50: I also found that tablets were in effective and nothing I can do except use nasal spray which works a ton better when you wake up with a blocked nose every morning (Thanks to @satanboy )

EDIT: Nasal spray I use as an equivalent in the UK is Fluticasone Propionate
 

biometrics

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Same. Used to get hayfever every damn year from end Sept. Bad. Needed injection since tabs were ineffective. Then all of a sudden it stopped for 3 years until now. Eyes and nose burning and itching, sneezing uncontrollably...
Fuck! I hate this
I used to get hayfever very badly as a youngster. When I moved from Stellenbosch to Cape Town at age 20 it suddenly stopped. My theory is that there were more pollution in the air that bonded with the pollen. But problem just outgrew it.
 

satanboy

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used to get hayfever very badly as a youngster. When I moved from Stellenbosch to Cape Town at age 20 it suddenly stopped. My theory is that there were more pollution in the air that bonded with the pollen. But problem just outgrew it.
I never had it and suddenly it started 5 years back (+/-).
 
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Spizz

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Her*anus
Cetrizine hydrochloride for the win. Been taking for years now but usually only needed for about 2 months in springtime.
 
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